Figure 1 (IMAGE)
Caption
Osmotic pressure-and-viscosity-modified Docetaxel via lymphatic drug delivery system (LDDS) can inhibit tumor growth in the lymphatic system and prevent distant metastasis. Increases in osmotic pressure and viscosity lead to significant tumor inhibition in the sentinel lymph node (LN) and its' downstream LN. Moreover, we found the underlying mechanism of increased osmotic pressure and viscosity using Cisplatin (CDDP). The optimal range of osmotic pressure and viscosity solution covers all areas of its downstream LN via LDDS.
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Tohoku University
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