Flow diagram of this study. (IMAGE) China Anti-Cancer Association Caption Flow diagram of this study. Flow diagram shows the analytic process of the DRIA predictive value in multiple ICI-treated cohorts. DRIA, DNA damage response-related immune activation; ICIs, immune checkpoint inhibitors; GI, gastrointestinal; MSS, microsatellite-stable. Credit Cancer Biology & Medicine Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.