Cells lacking FIGNL1, a specialized enzyme, manifest abnormal chromosome bridges between pairs of chromosomes during cell division (IMAGE)

Kindai University

Cells lacking FIGNL1, a specialized enzyme, manifest abnormal chromosome bridges between pairs of chromosomes during cell division

Caption

The above representative microscope images showcase ultra-fine bridges, a kind of abnormal link between chromosomes that causes catastrophic genetic instability. These bridges, composed of entangled DNA, were observed in human cells lacking FIGNL1, cementing its role in the proper regulation of RAD51.

Credit

Professor Miki Shinoara from Kindai University

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License

CC BY

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