Role of miRNA21 in APAP-induced liver injury (IMAGE)

Xia & He Publishing Inc.

Role of miRNA21 in APAP-induced liver injury

Caption

Upregulation of miR21 during APAP hepatotoxicity inhibits hepatocyte proliferation by downregulating the β-catenin signaling pathway. Additionally, miR21 overexpression affects liver repair by inducing changes in gene expression, leading to the downregulation of autophagy and haemostasis. APAP, acetaminophen.

Credit

Monica Pibiri, Roberto Loi, Gabriella Simbula

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

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