A schematic diagram showing the Wnt signaling pathway in normal colonic epithelial cells and colon cancer cells (IMAGE)
Caption
APC, adenomatous polyposis coli; CBP, cAMP-response element binding protein; CIBP, calcium- and integrin-binding protein; CK, creatine kinase. CtBP, C-terminal binding protein; GRO, growth-regulated oncogene alpha; GSK, glycogen synthase kinase LRP5/6, low-density lipoprotein receptor-related protein (LRP)5 and 6; Tcf/Lef, T-cell factor/lymphoid enhancer factor.
Credit
Guo-Qing Chen, Si-Bao Chen, Rui-Hong Gong
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC