Mechanisms of immune evasion by lymphoma (IMAGE)
Caption
Major proposed mechanisms of immune evasion by lymphoma cells and the related molecules involved in each mechanism: “Hide” (MHC-I, MHC-II, CD58, CD54, CD80, CD86), “Defend” (CD95/FAS, BCL-2), “Immunosuppressive Microenvironment” (IL-10, Treg). BCL, B-cell lymphoma; CD, cluster of differentiation; IL, interleukin; MHC, major histocompatibility complex; NK, natural killer; Treg, regulatory T-cells.
Credit
Kamen W. Kossow
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CC BY-NC