Clu-GFP mice model in stem cell research (IMAGE)

The Institute of Medical Science, The University of Tokyo

Clu-GFP mice model in stem cell research

Caption

Clu-GFP mice enable tracking of aged hematopoietic stem cells (HSCs). The increasing abundance of Clu+ HSCs drives age-related changes in the stem cell population, while Clu– HSCs maintain more youthful characteristics. The changing balance between Clu+ and Clu– HSCs drives the core aging process in HSCs.

Credit

Professor Atsushi Iwama from the University of Tokyo, Japan

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