Researchers unravel novel regulatory mechanisms of host kinase mimicry by a conserved herpesvirus kinase (IMAGE)
Caption
Viruses have evolved various strategies to coexist and replicate within host cells. Mimicry of host proteins represents a key mechanism that ensures the prolonged persistence of herpesviruses in host cells. A new study by researchers from Japan sheds light on novel regulatory mechanisms of host cyclin-dependent kinase mimicry by a conserved herpesvirus kinase. Their findings demonstrate that phosphorylation of conserved residues in the viral kinase regulates viral replication, active lytic infection, and recurrence following latency.
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Prof. Yasushi Kawaguchi from The University of Tokyo, Japan
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