Restoration of Neuroestrogen Production Reduces Food Intake and Boosts MC4R Expression (IMAGE)

Fujita Health University

Restoration of Neuroestrogen Production Reduces Food Intake and Boosts MC4R Expression

Caption

Comparison of food intake and hypothalamic MC4R mRNA levels between aromatase knockout (ArKO) mice and brain-specific aromatase-restored (BrTG-ArKO) mice (n = 5 per group). The data show that reactivating neuroestrogen synthesis leads to a significant reduction in food consumption along with an increase in MC4R expression in the hypothalamus.

Credit

Takanori Hayashi from Fujita Health University School of Medicine Image source link: https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.17426

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