ATR–ATRIP Complex Interactions with Clinical Inhibitors (IMAGE)

Science China Press

ATR–ATRIP Complex Interactions with Clinical Inhibitors

Caption

Cryo-EM reconstructions of the human ATR–ATRIP complex show how clinical small-molecule inhibitors like VE-822 and RP-3500 bind to and inhibit ATR activity.

Credit

© University of Science & Technology of China

Usage Restrictions

Use with credit.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.