Biological clock representation of aging biomarker research (IMAGE)
Caption
Dr. Chia-Ling Kuo et al. demonstrate the Healthspan Proteomic Score (HPS), derived from chronological age and the expression levels of 86 proteins, is a strong predictor of disease and mortality risk. Lower HPS values are associated with higher risks of disease and mortality. Pictured is a “biological clock” representation hinting that proteins inform the HPS, which can inform our healthspan. Here, the clock’s hand is a 3D rendering of growth/differentiation factor 15 (GDF15), a protein predictor of healthspan. Image credit: Bernard L. Cook III, PhD, who conceptualized, illustrated, and composed the final image, and Illustrate, the software used to render GDF15 (Goodsell DS, Autin L, Olson AJ (2019) Illustrate: Software for Biomolecular Illustration. Structure 27, 1716-1720).
Credit
Image credit: UConn/Bernard L. Cook III, PhD
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