Eva1CAR-T cells can form more effective immune synapses (IMAGE)

Nagoya University

Eva1CAR-T cells can form more effective immune synapses

Caption

Due to the small size and height of the Eva1 molecule, Eva1CAR-T cells can form more effective immune synapses—contact zones between an immune cell and its target tumor cells. The formation of robust immune synapses improves signaling within CAR-T cells and ultimately leads to better cytokine production and proliferation of CAR-T cells. Cytokines help kill cancer cells and recruit other immune cells to fight the tumor.

Credit

Keiko Itano, Nagoya University

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License

CC BY

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