iPSC-derived microglia cells in a dish (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

iPSC-derived microglia cells in a dish

Caption

This image shows how human iPSCs in which the microglia-specifying six-TF cocktail is switched on (lower row), in contrast to iPSCs in which they remain switched off (upper row), abandon their pluripotency stage (marked by the protein OCT4) and adopt the fate of microglia cells (marked by the proteins CD11b, P2RY12, and CX3CR1).

Credit

Wyss Institute at Harvard University

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