PTGIR and T cells (IMAGE)
Caption
In many ways, T cells are like race cars. They require fuel to do their jobs and, when active for too long, can run out of energy. New findings from Van Andel Institute scientists and collaborators found a potential treatment target to reinvigorate dysfunctional or exhausted cells. Called PTGIR, this specialized molecule regulates T cell numbers and cancer-fighting powers. Too much PTGIR slams the brakes, limiting cells’ ability to combat cancer. Medications that block PTGIR may offer new opportunities to reenergize T cells and get them back in the race.
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Image by Gabrielle Eisma. Courtesy of Van Andel Institute.
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