New Tool Enhances CRISPR Accuracy by Accounting for Genetic Variants (IMAGE)

Pusan National University

New Tool Enhances CRISPR Accuracy by Accounting for Genetic Variants

Caption

Researchers introduce Variant-aware Cas-OFFinder, a web-based tool that improves CRISPR off-target predictions by incorporating individual genetic differences. By reconstructing allele-specific sequences, the tool offers haplotype-level insights, enabling safer and more precise genome editing in medicine, agriculture, and research.

Credit

Professor Jeongbin Park from Pusan National University, Korea

Usage Restrictions

Cannot be reused without permission

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.