Macromolecular Gene Delivery Systems: Advancing Non-viral Therapeutics with Synthetic and Natural Polymers (IMAGE)
Caption
Polymer-based gene delivery systems represent a promising class of non-viral vectors, offering significant advantages in safety, structural versatility, biodegradability, and the potential for targeted and controlled gene release. Both natural and synthetic polymers, as well as their hybrid forms, have been extensively explored to improve cellular uptake, endosomal escape, and transfection efficiency. Strategies such as surface modification with targeting ligands and integration of stimuli-responsive features have expanded their therapeutic potential.
Credit
Rajaram Mohapatra
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Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC