A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment (IMAGE)
Caption
Figure 1: 2B010 preferentially reacts with Treg expanded in vitro. CD4+CD25+, CD4+CD25−, and CD8+ T cells were isolated from human PBMCS by cell sorting and stimulated with anti-CD3/CD28 beads and IL-2. Cells were stained with Clone D1 or 2B010 on days 3, 5 and 7 after stimulation. One representative example of three different donors is shown.
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Copyright: © 2025 Buszko et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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