Untreated vs. treated cells (IMAGE)
Caption
The top row is untreated cancer cells and the bottom is chemotherapy treated. The left column is the whole nucleus while the right is zoomed into a portion of the nucleus. The untreated cells have larger clusters which correspond to chromatin packing, and the cells treated with chemotherapy have many clusters that are a lot smaller in size. Chemo-evasive cells have more packing domains and potentially more surface areas for enhanced gene expression.
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Vadim Backman Laboratory/Northwestern University
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