DNA damage in zebrafish liver tumour (IMAGE)

Walter and Eliza Hall Institute

DNA damage in zebrafish liver tumour

Caption

A section of liver tumour in a zebrafish shows liver cell DNA (cyan), cancer cells with KRAS activity (purple), and DNA damage (white). The study found that lowering a key protein involved in minor splicing causes DNA damage selectively in cancer cells, leading to the expression of the p53 tumour suppressor protein.

Credit

WEHI

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