Lower dose of abiraterone acetate as effective for prostate cancer treatment (IMAGE)

National University of Singapore

Lower dose of abiraterone acetate as effective for prostate cancer treatment

Caption

Clinical study design and research outcomes. (Bottom left) Low dose abiraterone acetate (AA) demonstrated reduced PSA levels-a marker of tumour activity. (Bottom middle) Safety profile suggested that low-dose AA was well tolerated during the 12-week treatment. (Bottom right) Modelling showed that even at half the usual dose of AA, over 80 per cent of the drug's target enzyme (CYP17A1) was still blocked.

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National University of Singapore

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