Multi-organ changes in pancreatic cancer cachexia (IMAGE)
Caption
This schematic illustration shows the major organs that are affected by and contribute to the development of pancreatic cancer cachexia. With pancreatic cancer at the center of the crosstalk network, the complex interactions between the organs are not only mediated by cachexia-inducing factors but also result from abnormalities in organ function and neuromodulation. Such an intertwined crosstalk network results in the formation of a vicious cycle, ultimately leading to intractable pancreatic cancer cachexia.
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hLife
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