TNFα-TNFR1 signaling induces pleiotropic responses i.e. activation of transcription factors viz. NF-κB and AP-1 to lead to cell proliferation or induction of apoptosis/necroptosis, depending upon the cellular environment (P: phosphorylated). (IMAGE)

FAR Publishing Limited

TNFα-TNFR1 signaling induces pleiotropic responses i.e. activation of transcription factors viz. NF-κB and AP-1 to lead to cell proliferation or induction of apoptosis/necroptosis, depending upon the cellular environment (P: phosphorylated).

Caption

TNFα-TNFR1 signaling induces pleiotropic responses i.e. activation of transcription factors viz. NF-κB and AP-1 to lead to cell proliferation

or induction of apoptosis/necroptosis, depending upon the cellular environment (P: phosphorylated).

Credit

P: phosphorylated

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