miRNA Dysregulation of AGE/RAGE Pathway in Metabolic Syndrome: A Novel Analysis Strategy Utilizing miRNA-profiling Data (IMAGE)

Xia & He Publishing Inc.

miRNA Dysregulation of AGE/RAGE Pathway in Metabolic Syndrome: A Novel Analysis Strategy Utilizing miRNA-profiling Data

Caption

miRNA dysregulation of AGE/RAGE signaling in the context of MetS and its comorbidities seems significant but insufficiently studied. Even with a deductive approach, one cannot help but notice that there are few data on the influence of miRNAs on important receptor genes for AGEs, especially on “non-canonical” ones, such as anti-RAGEs and scavenger receptors that capture AGEs, and also on their gene-encoded ligands, such as S100 proteins and HMGB1. 

Credit

Bograya Maria

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License

CC BY-NC

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