DNA repair with FEN1 knockdown and concurrent 53BP1 knockdown. (IMAGE)

Tokyo Metropolitan University

DNA repair with FEN1 knockdown and concurrent 53BP1 knockdown.

Caption

While the lack of FEN1 leads to accumulation of 53BP1, a lack of 53BP1 altogether allows other mechanisms to cleave the long flap and allow DNA repair to reach completion.

Credit

Tokyo Metropolitan University

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Credit must be given to the creator.

License

CC BY

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