Copper-Loaded Scaffolds for Targeted Treatment of Traumatic Brain Injury. (IMAGE)

Burns & Trauma

Copper-Loaded Scaffolds for Targeted Treatment of Traumatic Brain Injury.

Caption

Copper-Loaded Scaffolds for Targeted Treatment of Traumatic Brain Injury. This illustration shows the process of electrospinning copper oxide-loaded polycaprolactone (PCL) and gelatin (Gel) scaffolds (CuO@PG), which are implanted at the site of traumatic brain injury (TBI) in mice. The scaffold releases copper ions (Cu²⁺) to restore copper homeostasis, inhibiting pyroptosis through the regulation of key proteins such as ATP7A and CTR1, ultimately promoting neuroprotection and brain recovery.

Credit

Burns & Trauma

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CC BY-NC

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