Scientists build an “evolution engine” to rapidly reprogram proteins (IMAGE)

Scripps Research Institute

Scientists build an “evolution engine” to rapidly reprogram proteins

Caption

Schematic of the T7-ORACLE system. The genome is maintained by the non-mutagenic host replisome (gray), while an orthogonal T7 replisome (red) maintains only a dedicated plasmid (OR) at 100,000-fold elevated mutation rate.

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Scripps Research

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