Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer (IMAGE)
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Figure 1. Correlation between DNAmAge, AgeAccelDiff, and IEAA and chronological age by CRC status. (AgeAccelDiff, epigenetic age acceleration as departure of DNAmAge from chronological age; CRC, colorectal cancer; DNAmAge, DNA methylation–based marker of aging; IEAA, intrinsic epigenetic age acceleration as residuals adjusted for cell composition). Horvath’s clock: (A) DNAmAge; (B) AgeAccelDiff; (C) IEAA. Hannum’s clock: (D) DNAmAge; (E) AgeAccelDiff; (F) IEAA. Levine’s clock: (G) DNAmAge; (H) AgeAccelDiff; (I) IEAA.
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