Cell Types Affected by Senescence in Skeletal Diseases (IMAGE)
Caption
This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, joints, and the spine—disrupting normal cell function and contributing to conditions such as osteoporosis, osteoarthritis, rheumatoid arthritis, intervertebral disc degeneration, ankylosing spondylitis, and bone tumors. Understanding which cells are involved is key to developing treatments that target the root causes of skeletal aging.
Credit
Dr. Sihan Hu from Yangzhou University, China Image Source Link: https://www.nature.com/articles/s41413-025-00448-7
Usage Restrictions
Credit must be given to the creator.
License
CC BY