Motor neurons (IMAGE)

University of Cologne

Motor neurons

Caption

Representative immunofluorescence image illustrating the neuroprotective effect of USP4 knockdown in iPSC-derived motor neurons (green) carrying an ALS-linked mutation. Inhibition of USP4 (EPS8 signaling partner) prevents the neurodegeneration (yellow) normally induced by the ALS mutation.

Credit

Seda Koyuncu

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