The mechanism of δ-VB/SCFAs/LPS on TLR-4/MyD88/NF-κB pathway in high glucose-induced bEnd.3 cells. (IMAGE)
Caption
(a) Correlation analysis between δ-VB/SCFAs/LPS and Gal-3 in vivo after BBR treatment. (b) Gal-3 in bEnd.3 cells after treatment (n = 6). (c) TLR-4 in bEnd.3 cells after treatment (n = 6). (d) MyD88 in bEnd.3 cells after treatment (n = 6). (e) p-P65/P65 of NF-κB in bEnd.3 cells after treatment (n = 6). (f) TNF-α in bEnd.3 cells after treatment (n = 6). (g) IL-1β in bEnd.3 cells after treatment (n = 6). (h) IL-6 in bEnd.3 cells after treatment (n = 6). Statistical analysis was performed with one-way ANOVA followed by Dunnett-t test (*P < 0.05, **P < 0.01, ***P < 0.001).
Credit
Zheng-Wei Zhang, Wei-Ping Wang, Jia-Chun Hu, Jin-Yue Lu, Ru Feng, Shao-Feng Xu, Ling Wang, Jie Fu, Hang Yu, Hui Xu, Hao-Jian Zhang, Xin-Yu Yang, Zhao Zhai, Jing-Yue Wang, Meng-Liang Ye, Heng-Tong Zuo, Jian-Ye Song, Yi Zhao, Xiang Hui, Xiao-Liang Wang, Jian-Dong Jiang, Yan Wang
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