Newly synthesized vitamin K analogues cross the blood-brain barrier and induce neuronal differentiation (IMAGE)

Shibaura Institute of Technology

Newly synthesized vitamin K analogues cross the blood-brain barrier and induce neuronal differentiation

Caption

Researchers from Shibaura Institute of Technology have designed and synthesized novel vitamin K analogues conjugated with retinoic acid, which exhibit potent neuronal differentiation-inducing activities. Their findings highlight unique mechanisms underlying the neuroprotective effects of vitamin K and its analogues, paving the way for the development of effective treatments against neurodegenerative diseases.

Credit

Associate Professor Yoshihisa Hirota, Shibaura Institute of Technology, Japan Source Link: https://pubs.acs.org/doi/full/10.1021/acschemneuro.5c00111

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