Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction (IMAGE)

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Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction

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Figure 6. Senescent heterogeneity model based on DNA content. Compared to G1-arrested cells, G2-arrested senescent cells express higher levels of senescence-associated markers, secrete more IL-6, and are more sensitive to senolytic treatments.

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Copyright: © 2025 Neri et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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