Co-designing Approaches to Sustainable Exercise Care for People with Metabolic Dysfunction-associated Steatotic Liver Disease (IMAGE)

Xia & He Publishing Inc.

Co-designing Approaches to Sustainable Exercise Care for People with Metabolic Dysfunction-associated Steatotic Liver Disease

Caption

The disconnect between research priorities of hepatologists, exercise professionals, and people with MASLD highlights the critical importance of community and consumer involvement throughout all phases of research design and delivery. Key clinical recommendations include: (i) Patient-important outcomes should be assessed and prioritized in research concerning exercise and MASLD management. (ii) The benefits of exercise on patient-important outcomes should be highlighted in exercise conversations. (iii) Exercise research should include standardized non-invasive outcomes of liver histology and appropriately assess and report exercise adherence data to better inform dose-response relationships of exercise on histological outcomes. (iv) Research concerning exercise adherence-building strategies, which may include digital technologies, should be co-designed with lived experience partners. (v) Culturally responsive models of exercise care and point-of-care patient resources need to be defined, evaluated, and implemented across local, national, and global settings. (vi) Training in exercise-related care should be embedded in the curricula and professional development of medical practitioners and clinicians involved in MASLD care.

There is a need to address the priorities of people with MASLD in ongoing research. Exercise and diet intervention studies are well placed for hybrid implementation-effectiveness trials, which have co-primary aims to investigate the effectiveness of type and dose of exercise along with implementation strategies to overcome non-liver barriers such as access, cost, and complex lives with competing priorities. Co-design at each stage of the research lifecycle is vital to advance the awareness and management of MASLD.

Credit

Shelley E. Keating

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CC BY-NC

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