EBLNP comparison to PEGLNP (IMAGE)

National University of Singapore, Yong Loo Lin School of Medicine

EBLNP comparison to PEGLNP

Caption

An albumin-recruiting lipid nanoparticle (EB-LNP) formulation promotes lymphatic drainage while avoiding liver accumulation compared to traditional LNP system (PEG-LNP). a, The molecular complex formed between EB-lipid and albumin. EB-lipid was employed to prepare EB-LNP using microfluidic device. b, In vivo fluorescence imaging of mice following intramuscular injection of EB-LNP or PEG-LNP labelled with a near-infrared probe, demonstrating the different biodistribution and tissue accumulation.

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NUS Medicine

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