Integrase illustration (IMAGE)
Caption
On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is integrase in its simpler four-part complex (pink), as it interacts with viral RNA (green) inside an HIV capsid.
Credit
Salk Institute
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License
Original content