TST inhibitor suppressed RMS growth in vivo. (IMAGE)
Caption
TST inhibitor suppressed RMS growth in vivo. (A) TST, CTX, and control group of tumor-bearing mice. (B) Tumor size growth curve of tumor-bearing mice in 3 groups. (C) Effects of TST on tumors in tumor-bearing mice and the two other groups. (D) TRITC and FITC labeled immunofluorescence TUNEL images of 3 groups. (E) The apoptosis rate histogram of RMS cells in vivo in 3 groups. (F) The toxicity of TST on organs of tumor-bearing mice of 3 groups. ns: p > 0.05, *: p < 0.05, **: p < 0.01, ***: p < 0.001, ****: p < 0.0001. CTX, cyclophosphamide; FITC, fluorescein isothiocyanate; TRITC, tetramethylrhodamine; TST, thiostrepton; TUNEL, terminal deoxynucleotidyl transferase dUTP nick-end labeling.
Credit
Pediatric Discovery
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