Immunofluorescence analysis (IMAGE)
Caption
Immunofluorescence analysis revealed that subsets of PDGFRα⁺ oligodendrocyte precursor cells (OPCs) accumulating at the peri-infarct border exhibited upregulated HIF-1α and CXCR4 expression 3–5 days after transient middle cerebral artery occlusion. These findings highlight the emergence of “angiogenic” OPCs, a distinct population that may contribute to vascular remodeling and tissue repair under hypoxic conditions following ischemic stroke. Scale bar = 50 μm.
Credit
Kuwata, Yasuda, Tsukita, Kikuya, Takayama, Maki, et al., Kyoto University Graduate School of Medicine
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Credit must be given to the creator. Adaptations must be shared under the same terms.
License
CC BY-SA