A promising molecule against chemotherapy-induced neuropathies (IMAGE)
Caption
Microscope images showing fine nerve endings in the hind leg skin of rats following a treatment with two molecules: paclitaxel, a chemotherapy drug, and Carba1, a molecule that protects the nerves. The nerve fibres (in green, indicated by white arrows) extend from the deep layers to the surface of the skin. Their number decreases significantly after treatment with paclitaxel, a chemotherapy drug known to damage nerves. However, these fibres are largely preserved when the neuroprotective molecule (Carba1) is administered at the same time as the paclitaxel.
Scale bar: 100 micrometres (µm).
Credit
© Science Advances/ David Balayssac
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