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Proteogenomics and their applications in target cancer therapy research. The application of proteogenomics (mainly including genomics, transcriptomics, and proteomics) has become an indispensable tool in the diagnosis and treatment of various types of cancer. Through the assessment of alterations, molecular expressions, cell populations, sample subtyping, and other aspects, proteogenomics can provide invaluable insights into preclinical target cancer therapy research. This includes unraveling the mechanism of tumorigenesis, identifying potential targets and specific biomarkers, and predicting subtype-specific therapy
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Yuying Suo, Yuanli Song, Yuqiu Wang, Qian Liu, Henry Rodriguez, Hu Zhou
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