Support cells in the brain called astrocytes (green) increase their levels of STAT3 activation (pSTAT3, magenta) in a mouse model of dementia. (IMAGE)

Weill Cornell Medicine

Support cells in the brain called astrocytes (green) increase their levels of STAT3 activation (pSTAT3, magenta) in a mouse model of dementia.

Caption

Support cells in the brain called astrocytes (green) increase their levels of STAT3 activation (pSTAT3, magenta) in a mouse model of dementia. This promotes changes in gene expression and inflammation associated with disease. Blocking Complex III ROS suppresses astrocytic pSTAT3 and reduces brain pathology.

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Credit: Daniel Barnett

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