Single-cell analysis reveals new HPV-linked keratinocyte subtype driving early cervical cancer (IMAGE)

Chinese Medical Journals Publishing House Co., Ltd.

Single-cell analysis reveals new HPV-linked keratinocyte subtype driving early cervical cancer

Caption

Researchers from Xinjiang Medical University used single-cell RNA sequencing to identify PI3+S100A7+ keratinocytes in early-stage HPV-positive cervical cancer. These cells interact closely with immune macrophages, reshaping the tumor microenvironment and contributing to poor prognosis.

Credit

Professor Ruozheng Wang from The Affiliated Tumor Hospital of Xinjiang Medical University

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