Schematic representation of 3-step HER2-targeted 225Ac-PRIT (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

Schematic representation of 3-step HER2-targeted 225Ac-PRIT

Caption

Graphical Abstract: Schematic representation of 3-step HER2-targeted 225Ac-PRIT, 225Ac-PRIT treatment of BT-474 human breast cancer cell derived xenograft, and representative histologic images of kidneys stained with hematoxylin and eosin, taken from treated mice at 175 days (top: untreated control; bottom: 2 x 225Ac-PRIT [37 kBq + 37 kBq]).

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Image created by S. Rinne et al. Weil Cornell Medicine, New York, NY.

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