Nuclear pore complex transport barrier (VIDEO)

Rockefeller University

Caption

In situ model of the nuclear pore complex transport barrier: Tethered within the pore are highly dynamic protein threads termed FG Nups (green). Under physiological conditions, cargo-carrying transport factors (pink) interact with the FG Nups, loosely forming a central plug that helps organize a dynamic transport barrier. Selective transport may proceed preferentially through the surrounding region.

Credit

Lim lab

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