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Schematic of TIRF microscope set-up for vesicle clustering measurements. A,B Vesicle clustering caused by α-Syn (A) and representative TIRF image of vesicle clustering (B) of the following vesicle compositions: 12% DOPS + 20% DOPE + 48% DOPC + 0% CHOL (left) in the absence and (right) in the presence of 250 nmol/L α-Syn. C The enhancement in vesicle clustering caused by 250 nmol/L α-Syn in 12 mol% PS + variable mol% CHOL vesicles
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HIGHER EDUCATON PRESS
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