Inhibiting the neutrophil clock alters their position and activity in wounded tissue (IMAGE)
Caption
In the daytime (left), neutrophils (green) accumulate in tissue bordering the initial site of injury caused by heart attack–induced oxygen deprivation (region surrounded by the dotted line). However, treatment with a drug that inhibits the neutrophils’ internal clock and shifts them into nighttime mode (right) causes neutrophils to accumulate in the center of the initial wound, preventing them from damaging the surrounding tissue.
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©2025 Aroca-Crevillén et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20250240
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