Region-specific gene expression patterns in human cap-stage maxillary and mandibular tooth germs (IMAGE)

Tsinghua University Press

Region-specific gene expression patterns in human cap-stage maxillary and mandibular tooth germs

Caption

Representative images and heatmaps illustrate how human fetal tooth germs from the upper and lower jaws, although morphologically similar at the cap stage, already display distinct gene expression signatures. Maxillary tooth germs show higher expression of morphogenesis-related genes, while mandibular tooth germs are enriched for mineralization- and calcium homeostasis-related genes, highlighting early regional specialization in tooth development.

Credit

Oral Science and Homeostatic Medicine / Beijing Stomatological Hospital, Capital Medical University & Peking University School and Hospital of Stomatology

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