A working model of the SmWRKY32-SmbHLH65/SmbHLH85 regulation of tanshinone biosynthesis. (IMAGE)

Nanjing Agricultural University The Academy of Science

A working model of the SmWRKY32-SmbHLH65/SmbHLH85 regulation of tanshinone biosynthesis.

Caption

A working model of the SmWRKY32-SmbHLH65/SmbHLH85 regulation of tanshinone biosynthesis. SmWRKY32 binds to the SmbHLH65 promoter, suppressing its expression. SmbHLH65 positively regulates tanshinone biosynthesis by forming a complex with SmbHLH85, which promotes synthesis by increasing SmDXS2 and SmCPS1 transcription. Additionally, SmbHLH65 stimulates the expression of SmbHLH85. SmWRKY32 indirectly inhibits tanshinone biosynthesis by suppressing the activation complex formed by SmbHLH65 and SmbHLH85.

Image link: https://academic.oup.com/hr/article/12/7/uhaf096/8093018

Credit

Horticulture Research

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