Modeling Chronic Kidney Disease (CKD) Using Patient-Derived Tubuloids (IMAGE)

Institute of Science Tokyo

Modeling Chronic Kidney Disease (CKD) Using Patient-Derived Tubuloids

Caption

Researchers developed tubuloids from adult kidney cells. When exposed to cisplatin, the model replicated key steps in the chronic kidney disease progression, including DNA damage, cellular senescence, inflammation, and fibrosis.

 

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Institute of Science Tokyo

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