Ribosome competition drives selective degradation of suboptimal ribosomes (IMAGE)

The Institute of Medical Science, The University of Tokyo

Ribosome competition drives selective degradation of suboptimal ribosomes

Caption

Slower ribosomes stall during translation and collide with faster ones, triggering selective degradation of their small subunits. This “ribosome competition” mechanism ensures that only efficient ribosomes remain active, maintaining the accuracy and quality of protein synthesis within cells.

Credit

Assistant Professor Sihan Li, The Institute of Medical Science, The University of Tokyo, Japan

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