St. Jude scientists created Circularization for High-throughput Analysis of Nuclease Genome-wide Effects by Sequencing Base Editors (CHANGE-seq-BE), an unbiased, sensitive and resource-efficient method to find base editors’ off-target activity. (IMAGE)

St. Jude Children's Research Hospital

St. Jude scientists created Circularization for High-throughput Analysis of Nuclease Genome-wide Effects by Sequencing Base Editors (CHANGE-seq-BE), an unbiased, sensitive and resource-efficient method to find base editors’ off-target activity.

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(L) Corresponding author Shengdar Tsai, PhD, and (R) co-first author Varun Katta, both of the St. Jude Department of Hematology.

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Courtesy of St. Jude Children's Research Hospital

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